Thorne

Methyl-Guard

Active B-complex for methylation and homocysteine

Support cardiovascular, neurological, and cellular health with Methyl-Guard®, a comprehensive formula designed to optimize methylation — a critical biochemical process involved in DNA expression, detoxification, neurotransmitter production, and cardiovascular function.*

Methyl-Guard® provides the body with key methylation cofactors in their active, tissue-ready forms, including folate (5-MTHF), vitamin B12 (methylcobalamin), vitamin B6 (pyridoxal 5’-phosphate), and betaine. These nutrients help maintain healthy homocysteine levels, promote cognitive function, and support heart, bone, eye, and reproductive health — especially important for individuals with MTHFR genetic variants or age-related nutrient deficiencies.*

Key Benefits:

  • Supports healthy methylation, detoxification, and neurotransmitter function*
  • Helps maintain normal homocysteine levels to support heart and vascular health*
  • Promotes cognitive function, redox balance, and cellular repair*
  • Formulated for individuals with MTHFR gene mutations and aging-related methylation inefficiency*
  • Supports bone, eye, muscle, and female reproductive health*

Why You’ll Love It:

  • Contains 5-MTHF (bioactive folate), methylcobalamin (B12), P5P (B6), and betaine
  • Supports multiple systems including cardiovascular, neurological, and hormonal health*
  • Ideal for individuals with high homocysteine or methylation-related concerns*
  • Third-party tested for purity and ingredient integrity
  • 5-MTHF (bioactive folate)

    Methylcobalamin (Vitamin B12)

    Pyridoxal 5'-phosphate (P5P / active Vitamin B6)

    Betaine

Take 3 capsules two times daily or as recommended by your health-care practitioner.

To guarantee purity and product integrity, every item is shipped directly from the manufacturer’s own facility, never from bulk distributors or third-party storage. Shipping is always free, and your order never changes hands unnecessarily.

Because each brand fulfills its own orders, delivery times may vary. We partner with best-in-class wellness brands, each with their own shipping schedules, and you’ll receive tracking as soon as your order is on its way.

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Methyl-Guard

$56.00

$56.00

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